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Eric M Phizicky Selected Research

Anticodon

4/2022Identification of a Trm732 Motif Required for 2'-O-methylation of the tRNA Anticodon Loop by Trm7.
1/2018Lack of 2'-O-methylation in the tRNA anticodon loop of two phylogenetically distant yeast species activates the general amino acid control pathway.
12/2015Defects in tRNA Anticodon Loop 2'-O-Methylation Are Implicated in Nonsyndromic X-Linked Intellectual Disability due to Mutations in FTSJ1.
10/2012Yeast Trm7 interacts with distinct proteins for critical modifications of the tRNAPhe anticodon loop.

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Eric M Phizicky Research Topics

Disease

6Intellectual Disability (Idiocy)
04/2022 - 01/2015
1Dwarfism
09/2015
1Nervous System Diseases (Neurological Disorders)
01/2015
1Starvation
02/2013
1X-Linked Mental Retardation (Mental Retardation, X Linked)
10/2012

Drug/Important Bio-Agent (IBA)

5Transfer RNA (tRNA)IBA
04/2022 - 09/2015
4AnticodonIBA
04/2022 - 10/2012
2Phe Transfer RNAIBA
01/2018 - 01/2015
2Biological ProductsIBA
09/2015 - 01/2015
1Valine (L-Valine)FDA Link
10/2019
1InosineFDA Link
10/2019
1Methionine (L-Methionine)FDA Link
10/2019
15,6-dihydroxy-2-dimethylaminotetralin (M 7)IBA
09/2015
1His Transfer RNAIBA
02/2013
1UracilIBA
02/2013
1Glucose (Dextrose)FDA LinkGeneric
02/2013
1Proteins (Proteins, Gene)FDA Link
10/2012